Table 3. Factors Associated With Sustained Virological Response, Non-Response, and Relapse in Patients With Chronic Hepatitis C a.
Factor | SVR | Non-Response | Relapse | |||
---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
Age | NA | NA | 1.050 (1.008 - 1.094) | 0.020 b | NA | NA |
AST | 0.993 (0.987 - 0.999) | 0.032 b | NA | NA | NA | NA |
IL28B genotypes (CC/N-CC) | 6.977 (2.111 - 23.057) | 0.001 b | 0.199 (0.069 - 0.577) | 0.003 b | 0.102 (0.031 - 0.339) | < 0.001 b |
HCV genotypes (1,6/2,3) | 7.057 (1.165 - 42.748) | 0.033 b | NA | NA | NA | NA |
RVR (RVR/N-RVR) | 3.018 (1.075 - 8.476) | 0.036 b | NA | NA | 0.239 (0.078 - 0.738) | 0.013 b |
EVR (EVR/N-EVR) | 39.750 (8.561 - 184.565) | < 0.001 b | NA | NA | 0.102 (0.016 - 0.661) | 0.017 b |
a Abbreviation: AST, aspartate transaminase; EVR, early virologic response; IL28 CC, CC genotype of interleukin 28 single; OR, odds ratio; RVR, rapid virologic response; and NA, not applicable.
b Statistically significance was presented.