Figure 1.

Knock-out of TLR2 and NF-κB prevented Tregs elimination after nerve xenografting. (A) Flow cytometry analysis of CD4⁺Foxp3⁺ Tregs population in nerve allografts or xenografts. (B) Quantification of the CD4⁺Foxp3⁺ Tregs population from flow cytometry analysis. The CD4⁺Foxp3⁺ Tregs population was decreased after nerve xenografting compared to allografting. Data are representative of 3 experiments with similar results. (n=3-5, *p < 0.05 and **p < 0.01 vs corresponding allograft).