Skip to main content
. 2015 Aug 1;12(8):655–667. doi: 10.7150/ijms.12460

Figure 6.

Figure 6

Accumulation of ubiquitylated IκB. A. The total IκB levels were measured in kidney tissue homogenates of mice in four groups. Mice pretreated with 3MA (15 mg/kg) followed by challenge with by LPS (10 mg/kg) displayed significantly increased levels of IκB. After being co-immunoprecipitated with either antibody for p65 or with FK1, the LPS+3MA-treated mice displayed significantly higher levels of p65 (B) and FK1(C), demonstrating the binding of both ubiquitin and p65 to IκB in treated animals. *P<0.05 vs. CON; #P<0.05 vs. LPS.