Table 2.
Study | Randomization process | Estimation of sample size |
Allocation concealment | Intention to treat analysis |
Loss to follow-up |
Dropout | Jadad scores |
---|---|---|---|---|---|---|---|
NACT+RT vs. RT | |||||||
Cvitcovics et al. 7 1996 | Yes | Yes | No | Yes | Yes | Yes | 3 |
Chua et al. 8 1998 | Yes | Yes | No | Yes | No | Yes | 3 |
Ma et al. 9 2001 | No | Yes | No | Yes | Yes | Yes | 2 |
Hareyama et al. 10 2002 | Yes | No | No | Yes | Yes | Yes | 3 |
CCRT vs. RT | |||||||
Chan et al. 22,23 2002,2005 | Yes | Yes | No | Yes | No | Yes | 3 |
Kwong et al. 24 2004 | No | No | No | Yes | Yes | Yes | 2 |
Zhang et al. 25,26 2005,2013 | No | Yes | No | No | No | Yes | 2 |
NACT+CCRT vs. CCRT | |||||||
Hui et al. 12 2009 | Yes | Yes | No | Yes | No | Yes | 3 |
Fountzilas et al. 132012 | Yes | Yes | No | Yes | No | Yes | 3 |
NACT: neoadjuvant chemotherapy; CCRT: concurrent chemoradiotherapy; RT: radiotherapy.