Table 1. Association between EZH2 expression and the clinic-pathological characteristics of osteosarcoma patients.

Characteristics	EZH2 protein
	positive	Negative	Chi-square P-value
Age (years)			0.486
11~20	14	20
21~30	13	10
≥31	12	11
Gender			0.385
Male	24	29
Female	15	12
Grade			0.039*
Low	0	6
High	39	35
Stage			<0.01*
I	0	6
II	26	35
III	13	0
Local recurrence			0.334
Yes	9	6
No	30	35
Lung metastasis			<0.01*
Yes	13	0
No	26	41
Histological type			0.173
Osteoblastic	11	17
Chondroblastic	14	18
Fibroblastic	3	1
Others	11	5
tumor size			0.334
<10 cm	30	35
≥10 cm	9	6