Table 2.
No. | Approach | Molecular target | In vivo model | Effects | Ref. |
1 | PEI-GAL nano particles | ApoB | Normal mouse liver | Healthy liver targeting | 26 |
2 | PHEA-DEAEMA | E2F1 | - | HCC cell in vitro targeting | 27 |
3 | Inu-DETA | E2F1 | - | HCC cell in vitro targeting | 29 |
4 | Lipid-PEG | FVII | Normal mouse liver | Healthy liver targeting | 31 |
5 | pH-sensitive lipids | miRNA 122 | Normal mouse liver | Healthy liver targeting | 32 |
6 | US sensible lipids | BCL-2 | Mouse Xenograft HCC | HCC targeting | 33 |
PEI: Polyethyleneimine; DEAEMA: Diethylamino ethyl methacrylate; miRNA: Micro interfering RNA; HCC: Hepatocellular carcinoma.