Table I.
Characteristics of the patients with or without Candida-positive cultures.
| Classification | Candidemia, n (%) | Non-candidemia, n (%) | P-value | RR (95% CI) | Odds ratio (95% CI) |
|---|---|---|---|---|---|
| Clinical feature | |||||
| Fever | 13/19 (68.42) | 3/21 (14.28) | 0.0009c | 4.78 (1.61–14.27) | 13.00 (2.73–61.81) |
| Abdominal distention | 13/19 (68.42) | 2/21 (9.52) | 0.0001c | 7.18 (1.86–27.81) | 20.58 (3.58–114.40) |
| Vomiting | 12/19 (63.15) | 2/21 (9.52) | 0.0004c | 6.63 (1.70–25.91) | 16.29 (2.89–91.87) |
| Edema | 11/19 (57.89) | 4/21 (9.52) | 0.0211a | 3.04 (1.16–7.95) | 5.84 (1.41–24.18) |
| Serous effusion | 8/19 (42.10) | 2/21 (9.52) | 0.0281a | 4.42 (1.07–18.29) | 6.91 (1.24–38.53) |
| Tetter | 8/19 (42.10) | 1/21 (4.76) | 0.0072b | 8.84 (1.22–64.33) | 14.55 (1.60–132.00) |
| Thrush | 8/19 (42.01) | 0/21 (0.00) | 0.0010c | 31.78 (1.68–602.00) | |
| GI hemorrhage | 11/19 (57.89) | 1/21 (4.76) | 0.0003c | 12.16 (1.73–85.86) | 27.50 (3.03–249.60) |
| Pneumorrhagia | 5/19 (26.31) | 0/21 (0.00) | 0.0177a | 16.31 (0.84–318.40) | |
| Shock | 10/19 (52.63) | 2/21 (9.52) | 0.005b | 5.52 (1.38–22.10) | 10.56 (1.90–58.55) |
| Multiple organ failure | 9/19 (47.36) | 1/21 (4.76) | 0.0028b | 9.94 (1.39–71.41) | 18.00 (1.99–162.70) |
| Accompanying examination | |||||
| Leucocytes of >20×109/l | 11/19 (57.89) | 4/21 (19.05) | 0.0211a | 3.04 (1.16–7.95) | 5.84 (1.41–24.18) |
| Hb of <10 g/l | 14/19 (73.68) | 2/21 (9.52) | <0.0001c | 7.73 (2.01–29.72) | 26.60 (4.49–157.7) |
| Thrombocytopenia | 14/19 (73.68) | 3/21 (14.28) | 0.0003c | 5.16 (1.75–15.22) | 16.80 (3.41–82.64) |
| PCT of >2 ng/ml | 15/19 (78.94) | 7/21 (33.3) | 0.0051b | 2.37 (1.24–4.53) | 7.50 (1.78–31.29) |
| CRP of >50 mg/l | 14/19 (73.68) | 2/21 (9.52) | <0.0001c | 7.73 (2.01–29.72) | 26.60 (4.49–157.70) |
| Liver dysfunction | 14/19 (73.68) | 3/21 (14.28) | 0.0003c | 5.16 (1.75–15.22) | 16.80 (3.41–82.64) |
| Hypoproteinemia | 13/19 (68.42) | 4/21 (19.05) | 0.0109a | 3.25 (1.27–8.35) | 6.91 (1.70–28.04) |
| Other pathogens | |||||
| Bloodstream infections | 10/19 (52.63) | 2/21 (9.52) | 0.005b | 5.52 (1.38–22.10) | 10.56 (1.90–58.55) |
a
P=0.01–0.05
b
P=0.001–0.01
c
P<0.001. Results are expressed as numbers and constituent ratios of patients. GI, gastrointestinal; Hb, hemoglobin; PCT, procalcitonin; CRP, C-reactive protein; RR, relative risk; CI, confidence interval.