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. 2015 Jun 26;10(3):1149–1156. doi: 10.3892/etm.2015.2598

Table V.

Effects of CYP 3A5 and ABCB1 gene polymorphisms on creatinine clearance up to 24 months after transplantation as determined by bivariate linear regression.

Predictor Estimate P-value Model
CYP 3A5 (*1) −0.205 0.029 R=0.26, R2=0.07, P<0.05
ABCB1 (TT) −0.131 0.129

R2, proportion of the variance around the mean of creatinine clearance that is explained by the present model. CYP 3A5, cytochrome P450 3A5; ABCB1, ATP-binding cassette transporter B1.