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. 2015 Jan;135(1):59–67. doi: 10.1542/peds.2014-0628

TABLE 4.

Cox Regression Model Associations Between Maternal Depression Trajectory Group and Time of Onset of Health Risk Behaviors

Outcome Mild Maternal Depressive Symptoms (Trajectory Group 2) Maternal Depressive Symptoms During Adolescence (Trajectory Group 3) Maternal Depressive Symptoms During Midchildhood (Trajectory Group 4) Recurrent Maternal Depressive Symptoms (Trajectory Group 5)
Cigarette use, (95% CI) Crude 1.27* (1.02 to 1.57) 1.17 (0.77 to 1.77) 2.18** (1.52 to 3.13) 1.15 (0.80 to 1.67)
HRa
Adjustedb 1.25* (1.00 to 1.56) 1.01 (0.63 to 1.62) 2.15** (1.48 to 3.12) 0.92 (0.44 to 1.92)
HR
Alcohol use, (95% CI) Crude 1.15* (1.02 to 1.31) 0.96 (0.70 to 1.31) 1.37* (1.05 to 1.80) 1.16 (0.80 to 1.67)
Adjusteda 1.14 (0.99 to 1.31) 0.95 (0.68 to 1.34) 1.43* (1.05 to 1.96) 1.31 (0.87 to 1.98)
Alcohol use to intoxication, (95% CI) Crude 1.12 (0.93 to 1.36) 0.85 (0.57 to 1.26) 1.14 (0.7 to 1.88) 1.14 (0.67 to 1.94)
Adjusteda 1.03 (0.89 to 1.20) 0.90 (0.62 to 1.29) 1.28 (0.82 to 2.01) 1.04 (0.59 to 1.87)
Marijuana use, (95% CI) Crude 1.28* (1.05 to 1.57) 1.05 (0.72 to 1.53) 1.78* (1.10 to 2.86) 1.28 (0.71 to 2.32)
Adjusteda 1.24* (1.01 to 1.51) 0.99 (0.65 to 1.51) 1.91* (1.15 to 3.16) 1.33 (0.72 to 2.47)
Hallucinogen use, (95% CI) Crude 1.48 (0.93 to 2.38) 1.33 (0.70 to 2.53) 3.52* (1.32 to 9.38) 1.11 (0.01 to 238.74)
Adjusteda 1.52 (0.91 to 2.53) 1.04 (0.43 to 2.50) 3.51* (1.26 to 9.77) 1.12 (0.01 to 218.22)
Other drugs (eg, crack/cocaine) use, (95% CI) Crude 1.95** (1.25 to 3.03) 1.86 (0.94 to 3.69) 1.59 (0.63 to 4.01) 2.51 (0.09 to 69.53)
Adjusteda 1.77* (1.13 to 2.77) 1.23 (0.56 to 2.70) 1.43 (0.59 to 3.50) 1.59 (0.04 to 62.34)
Sexual intercourse, (95% CI) Crude 1.28* (1.01 to 1.62) 1.15 (0.78 to 1.69) 1.20 (0.69 to 2.08) 1.98* (1.04 to 3.79)
Adjusteda 1.26 (0.98 to 1.62) 1.00 (0.65 to 1.54) 1.28 (0.74 to 2.24) 1.86 (0.89 to 3.86)
*

P < .05. ** P < .005.

a

Results from Cox regression models with binary health risk behaviors and time of debut of these behaviors as outcomes, respectively. Hazard ratios compare trajectory groups 2, 3, 4, and 5 with group 1.

b

Adjusted for SES, gender, and cohort.