Table 3. Overlapped Reactome pathways between the two lung cancer studies across the top 20 pathways.

Pathway	Biological Functions	GSE10072		GSE7670
		NEES	FDR	NEES	FDR
Activation of the pre-replicative complex	DNA replication, cell cycle	3.36	<0.001	2.11	<0.001
DNA strand elongation	DNA replication, cell cycle	3.09	<0.001	2.44	<0.001
G2-M Checkpoints	cell cycle	3.04	<0.001	2.21	<0.001
Unwinding of DNA	DNA replication, cell cycle	3.03	<0.001	2.82	<0.001
Activation of ATR in response to replication stress	cell cycle	3.03	<0.001	2.17	<0.001
Condensation of Prometaphase Chromosomes	cell cycle	2.63	<0.001	2.42	<0.001
Polo-like kinase mediated events	cell cycle	2.45	<0.001	2.13	<0.001
Cyclin A-B1 associated events during G2-M transition	cell cycle	2.43	<0.001	2.13	<0.001
Collagen biosynthesis and modifying enzymes	extracellular matrix organization	2.22	<0.001	2.00	<0.001