Table 1.
Risk factors for the development of postoperative cerebral hyperperfusion
| Risk factors | Postoperative hyperperfusion |
P value | |
|---|---|---|---|
| Yes (n = 51) | No (n = 449) | ||
| Age (years) (mean ± SD) | 71.3 ± 5.8 | 68.7 ± 6.8 | 0.0128 |
| Male gender | 45 (88%) | 413 (92%) | 0.4195 |
| Hypertension | 46 (90%) | 378 (84%) | 0.3087 |
| Diabetes mellitus | 24 (47%) | 158 (35%) | 0.1238 |
| Dyslipidemia | 23 (45%) | 224 (50%) | 0.5565 |
| Symptomatic lesion | 39 (76%) | 275 (61%) | 0.0332 |
| Degree of ICA stenosis (%) (mean ± SD) | 91.3 ± 5.9 | 84.6 ± 8.8 | < 0.0001 |
| Bilateral lesion | 14 (27%) | 88 (20%) | 0.2001 |
| Duration of ICA clamping (min) (mean ± SD) | 36.8 ± 6.2 | 37.2 ± 5.3 | 0.6938 |
| Use of intraluminal shunt | 1 (2.0%) | 2 (0.4%) | 0.8776 |
| CBF at resting state (ml/100 g/min) | 24.3 ± 4.5 | 30.6 ± 7.3 | < 0.0001 |
| CVR to acetazolamide (%) | 9.2 ± 6.6 | 33.4 ± 15.4 | < 0.0001 |
CBF: cerebral blood flow, CVR: cerebrovascular reactivity, ICA: internal carotid artery, SD: standard deviation.