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The possibility of induced pluripotent stem (iPS) cell technology. Dopaminergic (DA) neurons from iPS cells of a Parkinson’s disease (PD) patient can be used for autologous cell transplantation, genetic/proteomic analyses for PD pathogenesis, and drug discovery/evaluation. DA neurons from iPS cells of a healthy volunteer can be used for allogeneic cell transplantation, analyses for PD pathogenesis after genetic manipulation, and drug discovery/evaluation.
