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. 2015 Jan 23;55(2):107–112. doi: 10.2176/nmc.ra.2014-0271

Fig. 3.

Fig. 3.

Immunostaining of Iba-1 (microglia/monocytes) clearly showing that transplanted stem cells inhibit migration of Iba-1-positive cells in the peri-infarct area. A: sham-operated animal, B: stem cell-transplanted animal. Asterisk indicates the ischemic core. The number of Iba-1-positive cells negatively correlated with the blood vessel density ratio (BVD), suggesting an interaction between neovascularization and the inflammatory response.