Table 2.
Multivariate analysis of risk factors for cerebral vasospasm
| Variable | AV grade III–IV |
Symptomatic vasospasm |
Cerebral infarction |
|||
|---|---|---|---|---|---|---|
| Odds ratio (95% CI) | p value | Odds ratio (95% CI) | p value | Odds ratio (95% CI) | p value | |
| Hunt-Hess grade III–IV | 0.98 (0.46–2.06) | 0.9705 | 0.88 (0.40–1.89) | 0.7589 | 1.30 (0.59–.2.84) | 0.5083 |
| SAH grade III–IV on CT scan | 9.09 (3.86–24.53) | < 0.0001 | 13.39 (5.15–42.49) | < 0.0001 | 7.64 (2.94–24.05) | 0.0001 |
| ICH or/and IVH on CT scan | 1.92 (0.78–4.73) | 0.1517 | 2.18 (0.87–5.54) | 0.0947 | 1.61 (0.65–3.93) | 0.2897 |
| Rebleeding | 1.14 (0.45–2.83) | 0.7722 | 0.92 (0.35–2.35) | 0.8765 | 1.16 (0.45–2.92) | 0.7457 |
| Current regular or former smokers | 2.77 (1.30–6.02) | 0.0086 | 2.83 (1.29–6.37) | 0.0099 | 2.84 (1.26–6.57) | 0.0123 |
| Hypertension | 1.92 (1.00–3.73) | 0.0485 | 2.06 (1.05–4.09) | 0.0347 | 2.18 (1.09–4.46) | 0.0284 |
| Daily drinkers | 1.23 (0.56–2.68) | 0.5933 | 0.80 (0.35–1.79) | 0.5991 | 0.62 (0.26–1.43) | 0.2701 |
| Count of WBC ≥ 10,000/mm 3 | 0.98 (0.49–1.95) | 0.9660 | 1.23 (0.60–2.52) | 0.5614 | 0.70 (0.33–1.45) | 0.3412 |
| Serum glucose level ≥ 130 mg/dl | 0.72 (0.31–1.71) | 0.4594 | 0.83 (0.34–2.05) | 0.6834 | 1.31 (0.52–3.57) | 0.5734 |
| QTc ≥ 450 ms on ECG | 1.52 (0.78–3.01) | 0.2209 | 1.02 (0.51–2.05) | 0.9391 | 1.44 (0.70–3.00) | 0.3191 |
| LVH on ECG | 2.71 (1.43–5.20) | 0.0023 | 3.48 (1.80–6.90) | 0.0003 | 2.19 (1.11–4.32) | 0.0224 |
| ST depression on ECG | 1.29 (0.56–2.90) | 0.5409 | 2.09 (0.91–4.78) | 0.0780 | 1.38 (0.59–3.12) | 0.4424 |
AV: angiographic vasospasm, CI: confidence interval, CT: computed tomography, ECG: electrocardiogram, ICH: intracerebral hemorrhage, IVH: intraventricular hemorrhage, LVH: left ventricular hypertrophy, SAH: subarachnoid hemorrhage, WBC: white blood cell.