Table 1.
Clinical characteristics of elderly and nonelderly patients
| ≥ 65 (n = 27) | < 65 (n = 49) | p value | |
|---|---|---|---|
| Age (mean ± SD) | 71.4 ± 3.8 | 47.1 ± 2.8 | |
| Sex | |||
| Male | 16 (59%) | 34 (69%) | 0.45 |
| Female | 11 (41%) | 15 (31%) | |
| KPS | |||
| < 70 | 8 (30%) | 7 (18%) | 0.37 |
| 70–100 | 19 (70%) | 31 (82%) | |
| RPA class | |||
| III | 10 (20%) | < 0.0001* | |
| IV | 3 (11%) | 25 (51%) | |
| V | 21 (78%) | 9 (18%) | |
| VI | 3 (11%) | 5 (10%) | |
| Extent of resection | |||
| GTR | 6 (22%) | 12 (24%) | 0.65 |
| PR | 16 (59%) | 24 (49%) | |
| Biopsy | 5 (19%) | 13 (27%) | |
| MGMT promoter | |||
| Methylated | 8 (42%) | 12 (41%) | 1.0 |
| Unmethylated | 11 (58%) | 17 (59%) |
*
Significant value. GTR: gross total removal, KPS: Karnofsky performance status, MGMT: O6-methylguanine methyltransferase, PR: partial removal, RPA: recursive partitioning analysis, SD: standard deviation.