Table II.

Expression of SMAD4 in association with clinicopathological characteristics.

	SMAD4 expression
Variable	Negative	Positive	P-value
Age, years			0.234
≤51	8	38
>51	4	37
Stage			0.993
I/II	7	43
III/IV	5	31
Histological grade			0.008
I	0	12
II	5	45
III	7	17
Tumor size			0.935
≤2 cm	3	12
>2 cm	9	62
Lymph node (n=48)			0.563
≤10	4	37
>10	1	6