EGFR-siRNA treatment inhibits Eca109 cell proliferation asdetermined by CCK-8 assay. OD values of Eca109 cell proliferation following transfection with EGFR-siRNA. Results are presented as mean ± standard deviation of four separate experiments (*P<0.05 vs. Control). NC, negative interference siRNA; PC, positive interference siRNA; Control, blank control group (untransfected); EGFR, epidermal growth factor receptor; siRNA, small interfering RNA; OD, optical density.