Protein expression of survivin and p-Rb in HCC and adjacent normal tissues. (A) Immunohistochemical analysis revealed that the HCC specimens exhibited evident nucleic protein expression of survivin and p-Rb, compared with that of adjacent noncancerous liver tissues (magnification, x400). (B) Quantification of survivin and p-Rb expression revealed enhanced expression in HCC tissues. (n=3, P<0.01). N, normal tissue; T, HCC tissue; p-Rb, phosphorylated retinoblastoma tumor suppressor; HCC, hepatocellular carcinoma.