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. 2015 Jun 24;36(3):669–677. doi: 10.3892/ijmm.2015.2259

Figure 1.

Figure 1

miR-135a and miR-135b are upregulated in injured podocytes. (A and B) Quantification by RT-qPCR of (A) miR-135a and (B) miR-135b expression in the isolated glomeruli from BALB/c mice treated with adriamycin (ADR; 10.5 mg/kg) at different time points after the injection (n=3, means ± SD). (C–F) miR-135a and miR-135b expression levels were measured in the cultured mouse podocyte cell line 5 (MPC5) treated with ADR (C and D) at different doses and (E and F) for different periods of time. (G) Quantification by RT-qPCR of miR-135a and miR-135b in the glomeruli isolated from 3 patients with focal segmental glomerulosclerosis (FSGS) and 3 patients with kidney rupture (controls). *P<0.05 and **P<0.01 indicacte statistically significant and highly statistically significant differences, respectively, compared with the controls. NO1, number 1 patient; NO2, number 2 patient; NO3, number 3 patient.