Table 3.
Plasma TAG, total cholesterol, and HDL levels after drug treatment. Colorimetric assays were performed to determine TAG, total cholesterol, and HDL in the plasma of the mice under various conditions as stated in the Methods section.
Treatment group | TAG | Total Cholesterol | HDL |
---|---|---|---|
Lean | 94.2 ± 5.9 | 93.5 ± 2.4 | 89.8 ± 10.1 |
HFD | 123.4 ± 6.7** | 157.0 ± 7.1**** | 196.3 ± 29.7** |
HFD + Vehicle | 110.9 ± 6.9 | 140.5 ± 6.6 | 213.9 ± 30.3 |
HFD + SRB | 104.4 ± 4.6 | 140.8 ± 6.0 | 200.2 ± 43.7 |
HFD + SR-135 | 101.6 ± 9.9 | 132.7 ± 8.1† | 271.5 ± 28.5 |
denotes a statistical significance between lean vs. HFD groups.
denotes a statistical significance between HFD vs. HFD + SR-135 groups.