Regional fat (as % of total) by skinfolds of children with lipodystrophy (LD+), possible LD, or no LD (LD−), as determined by clinician assessment. Children were classified as LD+, possible LD, and LD− if >2, 1, or 0 of features of lipoatrophy (i.e. sunken cheeks, temporal wasting, skinny limbs, wasting of buttocks) or lipohypertrophy (i.e increased abdominal girth, dorsal cervical enlargement, or breast enlargement) were present.