Fig. 4.

Confocal microscopy images of EMT-6 cells cultured under (a–d) normoxic and (g–j) hypoxic conditions using primary anti-lysyl oxidase (anti-LOX) monoclonal antibody (mAb) and a secondary Alexa Fluor 488 mAb. Cell nuclei were stained with 4′,6-diamidino-2-phenylindole. Control experiments in which (e, k) only the primary LOX mAb and (f, l) only secondary Alexa Fluor 488 mAb were used are shown