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. 2015 Aug 12;14:153. doi: 10.1186/s12943-015-0411-4

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© Rounge et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Small RNA contig expression in normal and TGCT samples. a Heatmap showing the expression data of the 2000 most highly expressed piRNAs (variance stabilization transformed data). The dendrogram (bottom) indicates clustering according to expression profiles. Heatmap colors represent relative small RNA contig expression as indicated in the color key (bottom right). b Volcano plot indicating the relationship between the Log2 fold change and p-values (Benjamini-Hochberg adjusted) for all small RNA contigs when comparing TGCT with normal samples. The CIS samples are included in the TGCT group. Color coding indicates the expression level as a function of normalized counts (BaseMean)