Table 3.

Cumulative 0.3 M NaCl and water intake by satiated and normovolemic rats that received bilateral injections of muscimol or saline into the LPBN combined with injection of losartan, atropine or vehicle in the tissue surrounding to the SFO.

Treatment	60 min	120 min	180 min	240 min
0.3 M NaCl intake (ml)
Vehicle tissue + saline LPBN	1.5 ± 1.3	1.6 ± 1.3	1.7 ± 1.3	1.7 ± 1.3
Vehicle tissue + muscimol LPBN	8.2 ± 4.8*	32.9 ± 4.3*	39.1 ± 4.3*	39.2 ± 4.3*
Losartan tissue + muscimol LPBN	9.6 ± 7.3	26.0 ± 7.2*	35.5 ± 5.4*	35.4 ± 4.2*
Atropine tissue + muscimol LPBN	10.6 ± 6.1	29.5 ± 3.7*	35.3 ± 4.2*	39.9 ± 5.4*
Water intake (ml)
Vehicle tissue + saline LPBN	0.8 ± 0.2	0.9 ± 0.2	1.0 ± 0.2	1.0 ± 0.2
Vehicle tissue + muscimol LPBN	1.5 ± 1.0	13.1 ± 1.8*	23.8 ± 1.2*	24.9 ± 1.4*
Losartan tissue + muscimol LPBN	2.4 ± 1.4	13.9 ± 2.6*	21.5 ± 1.2*	22.1 ± 1.5*
Atropine tissue + muscimol LPBN	2.4 ± 1.0	14.3 ± 1.5*	20.1 ± 1.3*	23.8 ± 1.9*

Results are reported as means ± SEM;

^*Different from vehicle tissue + saline LPBN; n = 6. Muscimol (0.5 nmol/0.2 μl); losartan (1 μg/0.1 μl); atropine (2 nmol/0.1 μl); vehicle (PBS, phosphate buffer saline).