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. Author manuscript; available in PMC: 2015 Aug 12.
Published in final edited form as: Pediatr Blood Cancer. 2013 Aug 31;61(2):238–244. doi: 10.1002/pbc.24686

Table II.

Summary of Pharmacokinetic Parameters for Mifamurtide*

Parameter Mean % CV
aAUC(0-inf) (hr.nmol/L) 21.6 34.9
bt ½ (hr) 2.04 22.3
cCL (mL/min) 1770 38.1
cCL (ml/min/m2) 1250 42.5
dVss (L) 287 45.4
dVss (L/m2) 211 54.5
eVz (L) 336 35.0
eVz(L/m2) 239 37.1
*

N=15 except t1/2 N=25.

a

AUC(0-inf): Area under the concentration-time curve from time zero extrapolated to infinity;

b

t1/2: terminal half-life;

c

CL clearance

d

Vss: volume of distribution at steady state;

e

Vz: terminal phase volume of distribution