Table 1.
List 1: identified proteins in human saliva
| Loc. | Swiss-Prot.-Nr. | Mat. | pMism. | Protein name |
|---|---|---|---|---|
| B | CHR14-ALC2 | 5 | pMism:7.51 | Ig alpha-2 chain C region was used to identify this gene |
| B | CHR5-MY10 | 6 | pMism:6.88 | Myosin X was used to identify this gene |
| B | CHR20-CAC24982 | 5 | pMism:8.84 | tr:cac24982: sequence 26 from patent wo0100806 precursor was used to identify this gene |
| A | CHR1-CAC32430 | 7 | pMism:10.65 | tr:cac32430: sequence 17 from patent wo0105971 was used to identify this gene |
| A | CHR12-CAD48670 | 7 | pMism:8.20 | tr:cad48670: sequence 1 from patent wo0229058 was used to identify this gene |
| A | CHR11-Q14697 | 9 | pMism:7.93 | tr:q14697: glucosidase II precursor (kiaa0088 protein) was used to identify this gene |
| A | CHR12-Q8N1N4 | 6 | pMism:7.53 | tr:q8n1n4: hypothetical protein FLJ39100 was used to identify this gene |
| A | CHR1-Q8N613 | 9 | pMism:9.63 | tr:q8n613: chromosome 1 open reading frame 10 was used to identify this gene |
| A | CHRX-Q8NG12 | 9 | pMism:12.95 | tr:q8ng12: premature ovarian failure 1b protein was used to identify this gene |
| A | CHR14-Q96HE7 | 8 | pMism:12.21 | tr:q96he7: ERO1 (S. cerevisiae)-like was used to identify this gene |
| A | SW:143S_HUMAN | 5 | pMism:11.49 | 14-3-3 protein sigma (stratifin) (epithelial cell marker protein 1) |
| A | SW:143Z_HUMAN | 6 | pMism:9.24 | 14-3-3 protein zeta/delta (protein kinase C inhibitor protein 1) |
| A | SW:GR78_HUMAN | 7 | pMism:8.88 | 78 kDa glucose-regulated protein precursor (GRP 78) |
| A, B | SW:ACTS_HUMAN | 5 | pMism:8.20 | Actin, alpha skeletal muscle (alpha-actin 1) |
| A, B | SW:ACTB_HUMAN | 9 | pMism:14.16 | Actin, cytoplasmic 1 (beta-actin) |
| A | SW:ARP3_HUMAN | 6 | pMism:8.94 | Actin-like protein 3 (actin-related protein 3) (actin-2) |
| A | SW:ADK_HUMAN | 5 | pMism:8.34 | Adenosine kinase (EC 2.7.1.20) (ak) |
| A | SW:SAHH_HUMAN | 6 | pMism:8.76 | Adenosylhomocysteinase (EC 3.3.1.1) |
| A | SW:ALDX_HUMAN | 4 | pMism:7.16 | Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) |
| A | SW:CRAB_HUMAN | 4 | pMism:10.61 | Alpha crystallin B chain (alpha(B)-crystallin) (rosenthal fiber component) |
| A, B | SW:ENOA_HUMAN | 9 | pMism:13.48 | Alpha enolase (EC 4.2.1.11) (2-phospho-d-glycerate hydro-lyase) |
| A, B | SW:ENOL_HUMAN | 5 | pMism:7.02 | Alpha enolase, lung specific (EC 4.2.1.11) |
| B | SW:A2HS_BOVIN | 6 | pMism:9.32 | Alpha-2-HS-glycoprotein precursor (Fetuin-a) (asialofetuin) |
| A | SW:AAC4_HUMAN | 8 | pMism:9.52 | Alpha-actinin 4 (non-muscle alpha-actinin 4) |
| B | SW:AMYC_HUMAN | 9 | pMism:9.61 | Alpha-amylase 2b precursor (EC 3.2.1.1) |
| A, B | SW:AMYS_HUMAN | 9 | pMism:13.68 | Alpha-amylase, salivary precursor (EC 3.2.1.1) |
| A | SW:ACTZ_HUMAN | 4 | pMism:10.27 | Alpha-centractin (centractin) (centrosome-associated actin homolog) |
| A | SW:ANX4_HUMAN | 9 | pMism:14.41 | Annexin A4 (annexin IV) (Lipocortin IV) (Endonexin I) |
| A | SW:ANX8_HUMAN | 1 | pMism:15.43 | Annexin A8 (annexin VIII) (vascular anticoagulant-beta) |
| A | SW:ANX1_HUMAN | 9 | pMism:17.87 | Annexin I (lipocortin I) (calpactin II) (chromobindin 9) (p35) |
| A | SW:ANX2_HUMAN | 9 | pMism:16.80 | Annexin II (lipocortin II) (calpactin I heavy chain) |
| A | SW:ANX3_HUMAN | 8 | pMism:12.81 | Annexin III (lipocortin III) (placental anticoagulant protein III) |
| A | SW:ANX6_HUMAN | 8 | pMism:11.62 | Annexin VI (lipocortin VI) (p68) (p70) (protein III) (chromobindin 20) |
| A, B | SW:AOP2_HUMAN | 6 | pMism:13.04 | Antioxidant protein 2 (1-cys peroxiredoxin) (1-cys Prx) |
| B | SW:APA1_HUMAN | 6 | pMism:9.19 | Apolipoprotein a-i precursor (Apo-AI) |
| A | SW:ATPA_HUMAN | 4 | pMism:7.38 | ATP synthase alpha chain, mitochondrial precursor (EC 3.6.3.14) |
| A | SW:ATPB_HUMAN | 7 | pMism:7.00 | ATP synthase beta chain, mitochondrial precursor (EC 3.6.3.14) |
| B | SW:ENOB_HUMAN | 6 | pMism:8.88 | Beta enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) |
| A | SW:PMGE_HUMAN | 6 | pMism:14.78 | Bisphosphoglycerate mutase (EC 5.4.2.4) |
| A, B | SW:S108_HUMAN | 4 | pMism:9.18 | Calgranulin A (migration inhibitory factor-related protein 8) (MRP 8) |
| A, B | SW:S109_HUMAN | 6 | pMism:11.89 | Calgranulin B (migration inhibitory factor-related protein 14) (MRP 14) |
| A, B | SW:CAH6_HUMAN | 8 | pMism:17.32 | Carbonic anhydrase VI precursor (EC 4.2.1.1) (carbonate dehydratase VI) |
| A | SW:DHCA_HUMAN | 6 | pMism:10.55 | Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 1) |
| B | SW:CATA_HUMAN | 10 | pMism:14.91 | Catalase (EC 1.11.1.6) |
| A | SW:CLI1_HUMAN | 8 | pMism:13.04 | Chloride intracellular channel protein 1 (nuclear chloride ion channel 27) |
| A | SW:CLI3_HUMAN | 6 | pMism:14.75 | Chloride intracellular channel protein 3 |
| A | SW:COF1_HUMAN | 4 | pMism:8.17 | Cofilin, non-muscle isoform (18 kDa phosphoprotein) (p18) |
| B | SW:CO3_HUMAN | 9 | pMism:8.91 | Complement C3 precursor [contains: C3a anaphylatoxin] |
| A, B | SW:CO1A_HUMAN | 7 | pMism:13.63 | Coronin-like protein p57 (coronin 1A) |
| A | SW:CYTB_HUMAN | 4 | pMism:8.79 | Cystatin B (liver thiol proteinase inhibitor) (CPI-B) (stefin B) |
| B | SW:CYTD_HUMAN | 4 | pMism:7.88 | Cystatin D precursor |
| A, B | SW:CYTS_HUMAN | 7 | pMism:16.66 | Cystatin S precursor (salivary acidic protein-1) (cystatin SA-III) |
| B | SW:CYTT_HUMAN | 6 | pMism:11.57 | Cystatin SA precursor (cystatin S5) |
| B | SW:CYTN_HUMAN | 5 | pMism:8.38 | Cystatin SN precursor (salivary cystatin SA-1) (cystain SA-I) |
| B | SW:CRS3_HUMAN | 4 | pMism:7.74 | Cysteine-rich secretory protein-3 precursor (CRISP-3) (SGP28 protein) |
| B | SW:DSC2_HUMAN | 8 | pMism:10.10 | Desmocollin 2A/2B precursor (desmosomal glycoprotein II and III) |
| A | SW:EML2_HUMAN | 6 | pMism:8.38 | Echinoderm microtubule-associated protein-like 2 (EMAP-2) |
| A | SW:EF11_HUMAN | 4 | pMism:8.12 | Elongation factor 1-alpha 1 (EF-1-alpha-1) (elongation factor 1 a-1) |
| A | SW:EFTS_NEIMA | 6 | pMism:9.75 | Elongation factor ts (EF-Ts) |
| A | SW:ER29_HUMAN | 5 | pMism:9.47 | Endoplasmic reticulum protein ERp29 precursor (ERp31) |
| A | SW:ECHM_HUMAN | 6 | pMism:9.15 | Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) |
| A | SW:IF32_HUMAN | 6 | pMism:11.90 | Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) |
| A, B | SW:CAZ1_HUMAN | 6 | pMism:14.51 | F-actin capping protein alpha-1 subunit (capZ alpha-1) |
| A | SW:CAZ2_HUMAN | 5 | pMism:14.83 | F-actin capping protein alpha-2 subunit (capZ alpha-2) |
| A | SW:CAPB_HUMAN | 5 | pMism:8.35 | F-actin capping protein beta subunit (capZ beta) |
| A | SW:FABE_HUMAN | 5 | pMism:10.80 | Fatty acid-binding protein, epidermal (E-FABP) |
| B | SW:FIBB_HUMAN | 8 | pMism:14.03 | Fibrinogen beta chain precursor. |
| A | SW:ALFA_HUMAN | 6 | pMism:10.30 | Fructose-bisphosphate aldolase a (EC 4.1.2.13) (muscle-type aldolase) |
| A | SW:LEG3_HUMAN | 5 | pMism:9.79 | Galectin-3 (galactose-specific lectin 3) (MAC-2 antigen) (IgE-binding protein) |
| A | SW:LEG7_HUMAN | 5 | pMism:8.58 | Galectin-7 (HKL-14) (PI7) |
| B | SW:GELS_HUMAN | 4 | pMism:7.50 | Gelsolin precursor, plasma (actin-depolymerizing factor) (ADF) |
| A | SW:GLNA_HUMAN | 4 | pMism:8.41 | Glutamine synthetase (EC 6.3.1.2) (glutamate-ammonia ligase) |
| A, B | SW:GTP_HUMAN | 8 | pMism:14.25 | Glutathione S-transferase p (EC 2.5.1.18) (GST class-pi) |
| B | SW:GSHB_HUMAN | 8 | pMism:13.37 | Glutathione synthetase (EC 6.3.2.3) (glutathione synthase) |
| A | SW:G3P2_HUMAN | 4 | pMism:7.38 | Glyceraldehyde 3-phosphate dehydrogenase, liver (EC 1.2.1.12) |
| A | SW:GBLP_HUMAN | 7 | pMism:10.08 | Guanine nucleotide-binding protein beta subunit-like protein 12.3 (p205) |
| A, B | SW:HS27_HUMAN | 7 | pMism:13.08 | Heat shock 27 kDa protein (HSP 27) (stress-responsive protein 27) |
| A, B | SW:HS71_HUMAN | 8 | pMism:13.76 | Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2) |
| B | SW:HS76_HUMAN | 6 | pMism:9.56 | Heat shock 70 kDa protein 6 (heat shock 70 kDa protein B′) |
| A, B | SW:HS7C_HUMAN | 9 | pMism:13.07 | Heat shock cognate 71 kDa protein |
| B | TR_HUM:AAN65630 | 6 | pMism:6.93 | Hepatocellular carcinoma associated protein TB6 |
| A | SW:YHU6_YEAST | 6 | pMism:7.80 | Hypothetical 51.1 kDa protein in DCD1-MRPL6 intergenic region |
| A | TR_HUM:Q8N1N4 | 5 | pMism:7.81 | Hypothetical protein FLJ39100 |
| B | SW:ALC1_HUMAN | 6 | pMism:13.03 | Ig alpha-1 chain C region |
| B | SW:ALC2_HUMAN | 6 | pMism:9.44 | Ig alpha-2 chain C region |
| B | SW:GC1_HUMAN | 5 | pMism:8.28 | Ig gamma-1 chain C region |
| B | SW:KAC_HUMAN | 4 | pMism:8.20 | Ig kappa chain C region |
| B | SW:MUC_HUMAN | 7 | pMism:10.04 | Ig mu chain C region |
| B | SW:MUCB_HUMAN | 5 | pMism:7.55 | Ig mu heavy chain disease protein (bot) |
| B | TR_HUM:AAB3083 | 5 | pMism:8.13 | Immunoglobulin A heavy chain allotype 2 (fragment) |
| B | SW:IGJ_HUMAN | 4 | pMism:7.78 | Immunoglobulin J chain |
| A | SW:IL1X_HUMAN | 4 | pMism:8.29 | Interleukin-1 receptor antagonist protein precursor (IL-1ra) |
| A | SW:PLAK_HUMAN | 4 | pMism:8.04 | Junction plakoglobin (desmoplakin III) |
| A | SW:K1CM_HUMAN | 9 | pMism:11.83 | Keratin, type I cytoskeletal 13 (cytokeratin 13) (K13) (CK 13) |
| A | SW:K1CN_HUMAN | 9 | pMism:10.83 | Keratin, type I cytoskeletal 14 (cytokeratin 14) (K14) (CK 14) |
| A | SW:K1CO_HUMAN | 6 | pMism:8.17 | Keratin, type I cytoskeletal 15 (cytokeratin 15) (K15) (CK 15) |
| A | SW:K1CP_HUMAN | 6 | pMism:8.48 | Keratin, type I cytoskeletal 16 (cytokeratin 16) (K16) (CK 16) |
| A | SW:K22E_HUMAN | 5 | pMism:6.69 | Keratin, type II cytoskeletal 2 epidermal (cytokeratin 2e) |
| A | SW:K22O_HUMAN | 8 | pMism:11.65 | Keratin, type II cytoskeletal 2 oral (cytokeratin 2p) |
| A | SW:K2C3_HUMAN | 7 | pMism:8.91 | Keratin, type II cytoskeletal 3 (cytokeratin 3) (K3) (CK3) |
| A, B | SW:K2C4_HUMAN | 9 | pMism:8.81 | Keratin, type II cytoskeletal 4 (cytokeratin 4) (K4) (CK4) |
| A | SW:K2C5_HUMAN | 8 | pMism:8.38 | Keratin, type II cytoskeletal 5 (cytokeratin 5) (K5) (CK 5) |
| A | SW:K2CA_HUMAN | 9 | pMism:9.67 | Keratin, type II cytoskeletal 6a (cytokeratin 6a) (CK 6a) |
| A, B | SW:K2CB_HUMAN | 9 | pMism:9.16 | Keratin, type II cytoskeletal 6b (cytokeratin 6b) (CK 6b) |
| A | SW:K2CD_HUMAN | 8 | pMism:10.74 | Keratin, type II cytoskeletal 6d (cytokeratin 6d) (CK 6d) |
| A, B | SW:K2CE_HUMAN | 9 | pMism:9.76 | Keratin, type II cytoskeletal 6e (cytokeratin 6e) (CK 6e) |
| A | SW:K2CF_HUMAN | 6 | pMism:7.70 | Keratin, type II cytoskeletal 6f (cytokeratin 6f) (CK 6f) |
| A, B | SW:TRFL_HUMAN | 9 | pMism:9.42 | Lactotransferrin precursor (lactoferrin) |
| B | SW:ILEU_HUMAN | 6 | pMism:9.37 | Leukocyte elastase inhibitor (LEI) (monocyte/neutrophil elastase inhibitor) |
| A, B | SW:LKHA_HUMAN | 9 | pMism:14.08 | Leukotriene A4 hydrolase (EC 3.3.2.6) (LTA-4 hydrolase) |
| B | SW:PLSL_HUMAN | 7 | pMism:8.10 | L-plastin (lymphocyte cytosolic protein 1) (LCP-1) |
| A | SW:CAPG_HUMAN | 4 | pMism:7.59 | Macrophage capping protein (actin-regulatory protein CAP-G) |
| A | SW:MDHM_HUMAN | 7 | pMism:8.25 | Malate dehydrogenase, mitochondrial precursor (EC 1.1.1.37) |
| A | SW:MASP_HUMAN | 9 | pMism:12.66 | Maspin precursor (protease inhibitor 5) |
| A | SW:PRN3_HUMAN | 4 | pMism:11.33 | Myeloblastin precursor (EC 3.4.21.76) (leukocyte proteinase 3) |
| B | SW:MY10_HUMAN | 5 | pMism:7.16 | Myosin X |
| A | SW:NAGK_HUMAN | 7 | pMism:12.42 | N-acetylglucosamine kinase (EC 2.7.1.59) |
| B | SW:CYPH_HUMAN | 4 | pMism:7.34 | Peptidyl-prolyl cis-trans isomerase a (EC 5.2.1.8) (PPIase) |
| A | SW:PDX1_HUMAN | 8 | pMism:13.72 | Peroxiredoxin 1 (thioredoxin peroxidase 2) |
| A | SW:PDX2_HUMAN | 4 | pMism:11.27 | Peroxiredoxin 2 (EC 1.11.1.) (thioredoxin peroxidase 1) |
| A | SW:PDX5_HUMAN | 5 | pMism:10.87 | Peroxiredoxin 5, mitochondrial precursor (Prx-V) |
| A, B | SW:PMG1_HUMAN | 7 | pMism:11.60 | Phosphoglycerate mutase 1 (EC 5.4.2.1) (EC 5.4.2.4) |
| B | SW:PIGR_HUMAN | 9 | pMism:14.20 | Polymeric-immunoglobulin receptor precursor (poly-Ig receptor) |
| A | SW:PBEF_HUMAN | 5 | pMism:8.46 | Pre-B cell enhancing factor precursor |
| A, B | SW:PRO1_HUMAN | 6 | pMism:11.37 | Profilin I |
| A, B | SW:PIP_HUMAN | 6 | pMism:15.52 | Prolactin-inducible protein precursor (secretory actin-binding protein) |
| B | SW:PDI1_HUMAN | 6 | pMism:7.53 | Protein-arginine deiminase type I (EC 3.5.3.15) |
| A | SW:TGM3_HUMAN | 8 | pMism:10.61 | Protein-glutamine glutamyltransferase E precursor (EC 2.3.2.13) |
| B | SW:PNPH_HUMAN | 5 | pMism:8.02 | Purine nucleoside phosphorylase (EC 2.4.2.1) |
| A, B | SW:PDXK_HUMAN | 5 | pMism:8.21 | Pyridoxine kinase (EC 2.7.1.35) |
| A | SW:KPY1_HUMAN | 7 | pMism:8.89 | Pyruvate kinase, M1 isozyme (EC 2.7.1.40) |
| B | SW:GDIB_HUMAN | 8 | pMism:9.67 | Rab GDP dissociation inhibitor beta (Rab GDI beta) |
| A | SW:IQG1_HUMAN | 8 | pMism:8.74 | Ras GTPase-activating-like protein IQGAP1 (p195) |
| B | TR_HUM:CAC24982 | 5 | pMism:9.62 | Sequence 26 from patent wo0100806 precursor |
| A, B | SW:TRFE_HUMAN | 9 | pMism:9.41 | Serotransferrin precursor (transferrin) (siderophilin) |
| A, B | SW:ALBU_HUMAN | 9 | pMism:14.83 | Serum albumin precursor |
| A, B | SW:SCC1_HUMAN | 7 | pMism:8.98 | Squamous cell carcinoma antigen 1 (SCCA 1) |
| A | SW:GR75_HUMAN | 7 | pMism:12.04 | Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) |
| B | SW:SYNP_HUMAN | 4 | pMism:7.15 | Synphilin 1 (alpha-synuclein interacting protein) |
| A | SW:TKT_HUMAN | 5 | pMism:8.13 | Transketolase (EC 2.2.1.1) (TK) |
| A | SW:TPIS_HUMAN | 7 | pMism:11.79 | Triosephosphate isomerase (EC 5.3.1.1) (TIM) |
| A | SW:TBA1_HUMAN | 8 | pMism:16.58 | Tubulin alpha-1 chain (alpha-tubulin 1) |
| A | SW:TBA4_HUMAN | 7 | pMism:12.89 | Tubulin alpha-4 chain |
| A | SW:KCY_HUMAN | 4 | pMism:11.58 | UMP-CMP kinase (EC 2.7.4.14) (cytidylate kinase) |
| A | SW:POR1_HUMAN | 5 | pMism:10.28 | Voltage-dependent anion-selective channel protein 1 (VDAC 1) |
| A | SW:POR2_HUMAN | 5 | pMism:11.75 | Voltage-dependent anion-selective channel protein 2 (VDAC 2) |
| A | SW:WDR1_HUMAN | 5 | pMism:8.27 | WD-repeat protein 1 (actin interacting protein 1) |
| B | SW:ZA2G_HUMAN | 9 | pMism:13.3 | Zink-alpha-glycoprotein precursor |
A = epithelial cell debris, B = supernatant.