Table 1.
Most significant DEGs between PABs and SABs
| Gene Symbol | Description | Fold-change | p-value | FDR |
|---|---|---|---|---|
| Genes up-regulated in PAB | ||||
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 20.22 | 1.58E-11 | 3.17E-07 |
| WEE1 | WEE1 homolog (S. pombe) | 15.47 | 2.78E-03 | 6.62E-02 |
| ETV1 | ets variant 1 | 15.36 | 2.57E-09 | 1.43E-05 |
| HIST1H2BM | histone cluster 1, H2bm | 14.79 | 7.93E-09 | 3.30E-05 |
| SPC25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 13.44 | 1.18E-09 | 9.82E-06 |
| FAM177B | family with sequence similarity 177, member B | 11.90 | 4.67E-08 | 8.64E-05 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 11.83 | 6.02E-06 | 1.63E-03 |
| FAM111B | family with sequence similarity 111, member B | 11.67 | 5.55E-09 | 2.64E-05 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 11.41 | 3.36E-07 | 2.95E-04 |
| BIRC5 | baculoviral IAP repeat containing 5 | 10.78 | 3.03E-06 | 1.08E-03 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 10.78 | 1.90E-08 | 5.74E-05 |
| ETV5 | ets variant 5 | 10.48 | 1.42E-07 | 1.90E-04 |
| TOP2A | topoisomerase (DNA) II alpha 170 kDa | 10.48 | 6.66E-08 | 1.06E-04 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 10.41 | 1.78E-06 | 7.79E-04 |
| PLK4 | polo-like kinase 4 | 10.02 | 5.30E-05 | 6.03E-03 |
| CENPF | centromere protein F, 350/400 kDa (mitosin) | 9.81 | 6.31E-08 | 1.05E-04 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 9.39 | 8.76E-06 | 2.07E-03 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 9.33 | 6.40E-10 | 7.10E-06 |
| SNORD30 | small nucleolar RNA, C/D box 30 | 9.13 | 8.45E-04 | 3.23E-02 |
| FAM9A | family with sequence similarity 9, member A | 9.12 | 1.29E-08 | 4.76E-05 |
| RAD51AP1 | RAD51 associated protein 1 | 8.96 | 7.47E-07 | 4.69E-04 |
| CENPK | centromere protein K | 8.63 | 3.69E-07 | 3.15E-04 |
| DTL | denticleless homolog (Drosophila) | 8.60 | 2.70E-06 | 1.01E-03 |
| KIF11 | kinesin family member 11 | 8.53 | 1.59E-07 | 1.99E-04 |
| HELLS | helicase, lymphoid-specific | 8.32 | 2.52E-07 | 2.37E-04 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 8.18 | 1.96E-04 | 1.35E-02 |
| Genes up-regulated in SAB | ||||
| MMP20 | matrix metallopeptidase 20 | -26.41 | 9.20E-07 | 4.91E-04 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 | -21.58 | 6.42E-06 | 1.72E-03 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -18.49 | 1.24E-05 | 2.53E-03 |
| RGS13 | regulator of G-protein signaling 13 | -15.51 | 7.68E-06 | 1.94E-03 |
| SPHKAP | SPHK1 interactor, AKAP domain containing | -11.86 | 3.14E-05 | 4.59E-03 |
| ENAM | enamelin | -10.78 | 3.16E-03 | 7.06E-02 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -10.14 | 4.38E-06 | 1.34E-03 |
| LAMC2 | laminin, gamma 2 | -10.07 | 2.56E-05 | 4.10E-03 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | -10.02 | 1.47E-05 | 2.78E-03 |
| DSPP | dentin sialophosphoprotein | -9.32 | 1.41E-02 | 1.58E-01 |
| FAM20A | family with sequence similarity 20, member A | -9.13 | 8.58E-07 | 4.91E-04 |
| DMP1 | dentin matrix acidic phosphoprotein 1 | -8.73 | 4.71E-04 | 2.29E-02 |