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. 2015 Aug 12;13:186. doi: 10.1186/s12916-015-0426-0

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© D’Souza et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — MSC immunomodulatory properties in pancreatic regeneration. MSC are able to modulate the autoimmune response in T1D either by inducing regulatory T cells or by shifting the cytokine profile from a pro-inflammatory to an anti-inflammatory one. APC Antigen Presenting Cell, CTL Cytotoxic T Lymphocyte, Th1/2 T helper cell type 1/2, Treg regulatory T cell