Table 3. Median levels [95% confidence intervals] of oxidative stress markers according to placental pathologies.
Placental pathology | Oxidative Stress Marker (N = 120) | ||||
---|---|---|---|---|---|
MDA (mM/mg) | NO (mM) | SOD (SOD unit/mg) | CAT (μM of H2O2/min/mg) | GSH (mM/mg) | |
Parasites in the placenta (n = 16) | 1.40[1.16–1.71] | 0.07[0.05–0.12] | 80.39[55.5–86.1] | 1.42[1.04–3.01] | 55.37[52.3–66.0] |
No parasites in the placenta (n = 104) | 0.80[0.98–1.34] | 0.07[0.07–0.08] | 76.89[69.5–85.6] | 2.14[2.02–3.30] | 57.00[55.2–62.0] |
P | = 0.025 | = 0.80 | = 0.70 | = 0;78 | = 0.70 |
Leukocyte accumulation (n = 22) | 0.93[0.81–1.57] | 0.06[0.05–0.07] | 54.61[44.2–72.1] | 0.90[0.86–2.30] | 56.00[53.1–69.3] |
No leukocyte accumulation (n = 98) | 0.93[1.02–1.38] | 0.07[0.07–0.08] | 79.50[72.6–88.9] | 2.23[2.13–3.47] | 57.28[54.8–61.5] |
P | = 0.70 | = 0.046 | = 0.015 | = 0.09 | = 0.59 |
Presence of pigments (n = 15) | 1.40[1.13–1.98] | 0.08[0.05–0.13] | 84.67[58.4–94.1] | 1.90[1.07–3.97] | 60.00[55.2–74.5] |
Absence of pigments (n = 105) | 0.82[0.97–1.32] | 0.07[0.07–0.08] | 75.80[68.7–84.6] | 2.66[1.96–3.21] | 56.03[54.5–61.0] |
P | 0.021 | 0.37 | = 0.75 | 0.90 | 0.12 |
Values outside the bracket correspond to the median while values in brackets correspond to the lower and upper 95% confidence intervals, using Mann-Whitney Rank Sum test. MDA: Malondialdehyde; NO: nitric oxide; SOD: Superoxide dismutase, CAT: Catalase, GSH: Glutathione. P = p value