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. 2015 Aug 12;10(8):e0134633. doi: 10.1371/journal.pone.0134633

Table 3. Median levels [95% confidence intervals] of oxidative stress markers according to placental pathologies.

Placental pathology Oxidative Stress Marker (N = 120)
MDA (mM/mg) NO (mM) SOD (SOD unit/mg) CAT (μM of H2O2/min/mg) GSH (mM/mg)
Parasites in the placenta (n = 16) 1.40[1.16–1.71] 0.07[0.05–0.12] 80.39[55.5–86.1] 1.42[1.04–3.01] 55.37[52.3–66.0]
No parasites in the placenta (n = 104) 0.80[0.98–1.34] 0.07[0.07–0.08] 76.89[69.5–85.6] 2.14[2.02–3.30] 57.00[55.2–62.0]
P = 0.025 = 0.80 = 0.70 = 0;78 = 0.70
Leukocyte accumulation (n = 22) 0.93[0.81–1.57] 0.06[0.05–0.07] 54.61[44.2–72.1] 0.90[0.86–2.30] 56.00[53.1–69.3]
No leukocyte accumulation (n = 98) 0.93[1.02–1.38] 0.07[0.07–0.08] 79.50[72.6–88.9] 2.23[2.13–3.47] 57.28[54.8–61.5]
P = 0.70 = 0.046 = 0.015 = 0.09 = 0.59
Presence of pigments (n = 15) 1.40[1.13–1.98] 0.08[0.05–0.13] 84.67[58.4–94.1] 1.90[1.07–3.97] 60.00[55.2–74.5]
Absence of pigments (n = 105) 0.82[0.97–1.32] 0.07[0.07–0.08] 75.80[68.7–84.6] 2.66[1.96–3.21] 56.03[54.5–61.0]
P 0.021 0.37 = 0.75 0.90 0.12

Values outside the bracket correspond to the median while values in brackets correspond to the lower and upper 95% confidence intervals, using Mann-Whitney Rank Sum test. MDA: Malondialdehyde; NO: nitric oxide; SOD: Superoxide dismutase, CAT: Catalase, GSH: Glutathione. P = p value