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. 2015 Aug 12;10(8):e0135426. doi: 10.1371/journal.pone.0135426

Fig 5. Morphology of MCF-7 microtissues over time in culture.

Fig 5

MCF-7 cells aggregate into small groups forming microtissues following one day of growth (A, E) and have luminal spaces as early as 3 days in culture (B, F). Following 5 days in culture, luminal spaces are well developed and contain PAS-positive secretions (C, G). PAS-positive secretions continue to collect within the luminal spaces at 7 days (D, H). There is a lack of apoptotic debris in the luminal spaces of microtissues during this period. Scale bar = 50μm.