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. 2015 Jul 21;6(1):131. doi: 10.1186/s13287-015-0129-7

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© Micci et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — In vivo SPECT imaging of NIS-Hipp-NSCs injected in the brain hippocampus. Representative cross-sections of rat brain 2 weeks after transplantation of NIS-Hipp-NSCs or Hipp-NSCs in the hippocampus (CA1 region). Grafted cells are located on the basis of the expression of the cell tracker dye CMFDA. Mature neurons are identified on the basis of the expression of NeuN. Merged images show that some of the grafted cells express the neuronal marker NeuN (arrows). Cell nuclei are stained blue with DAPI. Scale bar = 50 μm. DAPI 4′,6-diamidino-2-phenylindole, Hipp-NSC hippocampus-derived neural stem cell, NIS-Hipp-NSC hippocampus-derived neural stem cell expressing the human sodium iodide symporter, SPECT single-photon emission tomography