Table 3.
Immunoglobulins and complement protein concentrations in colostrum and serum from normal weight, overweight and obese mothers
| Parameter | Normal weight | Overweight | Obese | Statistical | |
|---|---|---|---|---|---|
| IgA (g/L) | Colostrum | 3.3 (2.3-5.5) 3 | 3.8 (2.1-5.0) | 5.1 (3.3-9.6) 1,2,3 | F = 12.44; p = .001 (comparing the groups) |
| Serum | 2.2 (1.6-3.1) | 2.7 (2.2-3.5) | 3.9 (2.1-4.7) 1 | F = 21.69; p = .002 (comparing the colostrum and serum) | |
| IgM (g/L) | Colostrum | 1.3 (0.85-2.2) | 1.2 (0.8-2.1) | 1.4 (1.0-3.4) | F = 0.19; p = .825 (comparing the groups) |
| Serum | 1.3 (1.1-1.8) | 1.4 (0.8-2.4) | 1.0 (0.8-2.0) | F = 1.84; p = .177 (comparing the colostrum and serum) | |
| IgG (g/L) | Colostrum | 0.4 (0.1-0.6) 3 | 0.3 (0.2-0.5) 3 | 0.4 (0.2-0.6) 3 | F = 0.05; p = .947 (comparing the groups) |
| Serum | 11.3 (9.2-14.2) | 9.3 (8.5-16.7) | 10.8 (7.6-18.4) | F = 495.8; p = .001 (comparing the colostrum and serum) | |
| C3 (mg/dL) | Colostrum | 91.7 (50.5-110.2) 3 | 90.3 (44.1-97.9) 3 | 95.7 (41.3-130.9) 3 | F = 14.98; p = .001 (comparing the groups) |
| Serum | 121.1 (109.5-139.3) | 152.4 (90.6-250.0) | 249.8 (119.1-312.9) 1,2 | F = 117.30; p = .001 (comparing the colostrum and serum) | |
| C4 (mg/dL) | Colostrum | 30.1 (15.6-34.8) 3 | 24.2 (19.6-40.7) 3 | 28.8 (17.7-40.2) | F = 5.91; p = .040 (comparing the groups) |
| Serum | 16.4 (9.9-25.6) | 17.2 (7.1-25.8) | 22.9 (13.3-37.1) 1,2 | F = 20.68; p = .001 (comparing the colostrum and serum) |
Data presented as median, minimum and maximum values (within parentheses)
1Statistically significant differences in relation to the normal weight category, considering the same sample (colostrum or blood)
2Statistically significant differences in relation to the overweight category, considering the same sample (colostrum or blood)
3Statistically significant differences between colostrum and serum, considering the same group (normal weight, overweight and obese)