Table 1. Echocardiographic analysis of the left ventricle and transverse aorta at baseline and after two weeks of transverse aortic constriction (TAC).
Cont Baseline (n = 8) | Cont-TAC (n = 8) | MycKO Baseline (n = 8) | MycKO-TAC (n = 8) | |
---|---|---|---|---|
HR (BPM) | 512±24 | 540±12 | 507±19 | 541±12 |
TAC velocity (m/sec) | N/A | 4.8±0.2 | N/A | 4.6±0.1 |
EDD, mm | 4.1±0.1 | 3.9±0.1* | 4.2±0.1 | 3.9±0.1* |
ESD, mm | 2.9±0.1 | 2.6±0.1* | 2.9±0.1 | 2.7±0.1 |
FS, % | 29±2 | 32±2 | 31±1 | 30±1 |
ESD, mm | 55±3 | 61±3 | 59±2 | 58±2 |
HR, heart rate; BPM, beats per minute; EDD, left ventricular end diastolic diameter; ESD, left ventricular end systolic diameter; FS, left ventricular per cent fractional shortening; EF, left ventricular per cent ejection fraction; N/A, not applicable. Values are means±SEM.
* = p<0.05 versus baseline in the same group.