Table 2. Comparison of allelic frequencies between the normal controls and patients for each allele.
| Allele | Allelic frequencies of patients. | Patients(%) | Allelic frequencies of normal controls. | Normal(%) | P value |
|---|---|---|---|---|---|
| 46 | 2 | 0.05 | 0 | 0 | 1.000 |
| 45 | 2 | 0.05 | 0 | 0 | 1.000 |
| 44 | 7 | 0.2 | 1 | 0.1 | 1.000 |
| 43 | 8 | 0.2 | 2 | 0.2 | 1.000 |
| 42 | 17* | 0.4 | 3 | 0.3 | 1.000 |
| 41 | 48 | 1.1 | 8 | 0.8 | 0.289 |
| 40 | 41 | 0.98 | 8 | 0.8 | 0.527 |
| Total | 4198 | 100 | 1044 | 100 |
*There were 16 patients with 42 repeats, but TNR of the patient with 46 repeats(patient No.2 in S2 Table) was 46/42. So allelic frequency was counted as 17 in 42 repeats.
No.: Number of patients or controls.