Table 3. Comparison of allelic frequencies between the normal controls and patients by disease subtypes for each allele.
Allele | PD No (%) | MSA No (%) | Chorea No (%) | Other parkinsonism No (%) | Cerebellar ataxia No (%) | Normal No (%) |
---|---|---|---|---|---|---|
46 | 0 (0) | 1 (0.2) | 0 (0) | 1 (0.1) | 0 (0) | 0 (0) |
45 | 2 (0.1) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
44 | 2 (0.1) | 1 (0.2) | 0 (0) | 2 (0.2) | 2 (0.5) | 1 (0.1) |
43 | 4 (0.2) | 1 (0.2) | 0 (0) | 3 (0.3) | 0 (0) | 2 (0.2) |
42 | 7 (0.3) | 3 (0.5) | 2 (2.7)* | 3 (0.3) | 1 (0.2) | 3 (0.3) |
41 | 27 (1.3) | 7 (1.3) | 1 (1.4) | 9 (1.0) | 3 (0.7) | 8 (0.7) |
Total | 2138 | 556 | 74 | 898 | 440 | 1044 |
Allelic frequency of chorea with 42 repeats was significantly higher than that of the normal controls(*p = 0.033, analyzed with Fisher’s exact test)
No.: Number of patients or controls.