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MVA-induced Ca2+ spiking in HEK-293 cells expressing DMI1. (A and B) Absence of Ca2+ spiking in HEK-293 cells expressing the vector control pIRES2-YC3.6 in the absence (A) or presence of exogenous MVA (100 µM) (B). (C and D) Ca2+ spiking is only observed when MVA is added to HEK-293 cells expressing the pIRES2-YC3.6::DMI1 vector.
