Fig. S1.

Characteristics of the colon of Il10^−/−Sap1^−/−, Il10^−/−, Sap1^−/−, or WT mice. (A) Sections of the colon of WT or Sap1^−/− littermates at 20 wk of age were stained with Mayer’s H&E. (Scale bar, 100 μm.) (B) Body weight of male WT or Sap1^−/− mice at 20 wk of age. (C) Gross appearance of the colon from mice of the indicated genotypes at 20 wk of age. (Scale bar, 10 mm.) (D) The length (Left) and weight (Right) of the colon of Il10^−/− and Il10^−/−Sap1^−/− mice were measured at 20 wk of age. Data are representative of two independent experiments (A and C) and are from one representative experiment [B and D; means ± SEM for a total of three (B) or five (D) mice for each genotype]. *P < 0.05 (Student’s t test).