Fig. 5.

Trajectory of human schistosomiasis worm burdens and prevalence in a local population of 1,000 individuals under three control scenarios: MDA using praziquantel alone yearly for 5 y with 80% coverage (A and D), prawns maintained at a density of 0.25 per square meter for 20 y (B and E), or prawns maintained at a density of 0.25 per square meter and MDA applied in years 2 and 4 only (C and F). Thick, solid lines indicate the treated population (those participants who received praziquantel); thin, solid lines indicate the untreated population (those participants who did not receive praziquantel); and dashed lines indicate the mean population (including treated and untreated individuals). Arrows show the timing of MDA.