Fig. 1.

Green light illumination inhibits the activity of Arch-expressing auditory cortical neurons. (A) Mice were injected with AAV-CaMKII-Arch-EYFP and implanted with optical fibers in the auditory cortex (Au). (B) Arch-EYFP expression in the auditory cortex. (C and D) Green light illumination induced an outward current (C) and silenced action potentials (D) in Arch-expressing neurons. (E) Green light illumination decreased multiunit activities in the auditory cortex of anesthetized mice. (Upper) Representative raster plots of one channel. (Lower) Average normalized multiunit activities. Paired t test with Bonferroni correction, Pre vs. Light ON, t₇ = 3.8, *P = 0.0069. Error bars indicate mean ± SEM.