Table 1.

Tumor characteristics and the detection of CSF-tDNA

Patient	Diagnosis	Tumor grade	Tumor location	Location of CSF sampling	Tumor abutting CSF space	CSF-tDNA
CGLI 02	Glioma	WHO II, diffuse astrocytoma	T11 spinal cord	Spinal subarachnoid space	Yes	Not detected
CGLI 03	Anaplastic astrocytoma	WHO III, anaplastic astrocytoma	Pons	Basal cistern	Yes	Positive
CGLI 06	Pilocytic astrocytoma	WHO I, pilocytic astrocytoma	Cerebellar vermis	Basal cistern	Yes	Positive
CGLI 11	Spinal ependymoma	WHO II, ependymoma	C7-T3 spinal cord	Spinal subarachnoid space	Yes	Positive
CGLI 12	Intracranial ependymoma	WHO II, ependymoma	Fourth ventricle	Basal cistern	Yes	Positive
CGLI 13	Myxopapillary ependymoma	WHO I, myxopapillary ependymoma	L2-3 spinal cord	Spinal subarachnoid space	NA	Positive
CGLI 14	Intramedullary spinal cord lesion	Low-grade neoplasm	T7-9 spinal cord	Spinal subarachnoid space	Yes	Positive
CGLI 15	Spinal ependymoma	WHO II, ependymoma	C3-4 spinal cord	Spinal subarachnoid space	No	Not detected
CGLI 20	Medulloblastoma	WHO IV, medulloblastoma	Fourth ventricle	Basal cistern	Yes	Positive
CGLI 22	Pilocytic astrocytoma	WHO I, pilocytic astrocytoma	Cerebellar hemisphere	Basal cistern	No	Not detected
CGLI 25	Myxopapillary ependymoma	WHO I, myxopapillary ependymoma	L2-3 spinal cord	Spinal subarachnoid space	Yes	Positive
CGLI 26	Intramedullary spinal cord tumor	WHO II, infiltrating astrocytoma with oligodendroglial features	C3-6 spinal cord	Spinal subarachnoid space	Yes	Positive
CGLI 28	Anaplastic astrocytoma	WHO III, anaplastic astrocytoma	Right frontal/butterfly	Ventricle	Yes	Positive
CGLI 29	Glioblastoma	WHO IV, glioblastoma	C4-6 spinal cord	Spinal subarachnoid space	Yes	Positive
CGLI 31	Glioblastoma	WHO IV, glioblastoma	Right frontal/butterfly	Ventricle	Yes	Positive
CGLI 35	Glioblastoma	WHO IV, glioblastoma	Right temporal	Ventricle	Yes	Positive
CGLI 36	Spinal cord glioblastoma	WHO IV, glioblastoma	T10-L1 spinal cord	Spinal subarachnoid space	Yes	Positive
CGLI 39	Intramedullary spinal cord tumor	WHO II, low-grade glioma likely ependymoma	C2-3 spinal cord	Spinal subarachnoid space	No	Not detected
CGLI 40	Medulloblastoma	WHO IV, medulloblastoma	Fourth ventricle	Basal cistern	Yes	Positive
CGLI 41	Glioblastoma	WHO IV, glioblastoma	Cerebellar hemisphere	Basal cistern	Yes	Positive
CGLI 42	Spinal ependymoma	WHO II, ependymoma	T1-7 spinal cord	Spinal subarachnoid space	NA	Positive
CGLI 43	Low-grade glioma	WHO II, low-grade glioma	T10 spinal cord	Spinal subarachnoid space	Yes	Not detected
CGLI 44	Pilocytic astrocytoma	WHO I, pilocytic astrocytoma	Cerebellar vermis	Basal cistern	No	Not detected
CGLI 47	Glioblastoma	WHO IV, glioblastoma	Right temporal	Ventricle	Yes	Positive
CGLI 48	Glioblastoma	WHO IV, glioblastoma	Left temporal	Ventricle	Yes	Positive
CGLI 50	Glioblastoma	WHO IV, glioblastoma	Right temporal	Ventricle	Yes	Positive
CGLI 51	Glioblastoma	WHO IV, glioblastoma	Right frontal	Ventricle	Yes	Positive
CGLI 55	Brainstem glioblastoma	WHO IV, glioblastoma	Midbrain	Basal cistern	Yes	Positive
CGLI 56	Medulloblastoma	WHO IV, medulloblastoma	Fourth ventricle	Basal cistern	Yes	Positive
CGLI 58	Diffuse astrocytoma	WHO II, diffuse astrocytoma	T2-4 spinal cord	Spinal subarachnoid space	Yes	Not detected
CGLI 60	Medulloblastoma	WHO IV, medulloblastoma	Fourth ventricle	Basal cistern	Yes	Positive
CGLI 61	Pilocytic astrocytoma	WHO I, pilocytic astrocytoma	Cerebellar vermis	Basal cistern	Yes	Not detected
CGLI 63	Medulloblastoma	WHO IV, medulloblastoma	Cerebellum	Basal cistern	No	Not detected
CGLI 101	Glioblastoma	WHO IV, glioblastoma	Cerebellar vermis	Basal cistern	Yes	Positive
CGLI 254	Medulloblastoma	WHO IV, medulloblastoma	Fourth ventricle	Basal cistern	Yes	Positive

NA, not available.