Table 4.

Multivariate Modeling Output for Intrapatient Tacrolimus Trajectory for Acute Rejection and Interstitial Fibrosis/ Tubular Atrophy, Stratified by Race

Outcomea	Cohort	Parameter estimate	Standard error	Adjusted HR	95% CI	p value
Acute rejectionb	African-American	2.81	0.42	16.60	7.3–37.9	< 0.0001
	Non–African-American	1.54	0.30	4.65	2.58–8.36	< 0.0001
IF/TAc	African-American	2.07	1.81	7.91	0.23–275.3	0.2534
	Non–African-American	−1.21	3.89	0.30	0.00–609.3	0.7560

CI = confidence interval; HLA = human leukocyte antigen; HR = hazard ratio; IF/TA = interstitial fibrosis/tubular atrophy.

^aModel adjusted for gender, age, diabetes, insurance, donor type, HLA mismatch, panel reactive antibody, retransplant, and induction.

^bInteraction term p=0.0003.

^cInteraction term p=0.1823.