Cell cycle regulators |
p21 [55] |
Higher stage, recurrence, all-cause mortality |
p27 [56] |
Higher grade, cancer-specific mortality |
Ki67 [33] |
Recurrence, progression |
Cyclin D [55] |
Low grade, low stage, recurrence |
Cyclin E [55] |
Low stage, recurrence, cancer-specific mortality |
Apoptosis |
Survivin [32] |
Recurrence, cancer-specific mortality, all-cause mortality |
Bcl2 [8] |
Recurrence, cancer-specific mortality |
Caspase-3 [56] |
Recurrence, cancer-specific mortality |
Angiogenesis |
Micro-vessel density [57] |
Recurrence, all-cause mortality |
VEGF [58] |
Microvessel density, high grade, recurrence |
FGFR3 [60] |
Recurrence, cancer-specific mortality |
Tumor suppressor genes |
p53 [53] |
Higher stage, recurrence, progression, cancer-specific and all-cause mortality |
pRb [54] |
Higher stage, recurrence, progression, cancer-specific and all-cause mortality |
Proto-oncogenes & oncogenes |
EGFR [64] |
Higher grade, progression, all-cause mortality |
Her-2 Neu [64] |
Recurrence, metastasis, cancer-specific mortality |
FGFR3 [60] |
Low grade, low stage, recurrence and progression |
Miscellaneous |
GSTT1 [4] |
Recurrence, progression, cancer-specific mortality |
NOS & PPAR [65] |
Progression, cancer-specific mortality |
HMOX1 [66] |
Higher grade, recurrence and progression |