Table 1.
Top differentially up- and downregulated genes, sorted by significance of change.
| Upregulated genes | ||||||
|---|---|---|---|---|---|---|
|
| ||||||
| Ensmbl | Entrez | Gene | Gene name or description | Δ | p | |
| 1 | ENSG00000038427 | 1462 | VCAN | Versican | 4.5 | 7.40E-17 |
| 2 | ENSG00000175344 | 1139 | CHRNA7 | Cholinergic receptor, nicotinic, α7 (neuronal) | 13.3 | 2.50E-15 |
| 3 | ENSG00000189223 | 654433 | PAX8-AS1 | PAX8 antisense RNA 1 | 44.3 | 2.80E-12 |
| 4 | ENSG00000100181 | 387590 | TPTEP1 | Transmembrane phosphatase with tensin homology | 8.7 | 8.20E-12 |
| 5 | ENSG00000126709 | 2537 | IFI6 | Interferon, α-inducible protein 6 | 3.5 | 2.00E-11 |
| 6 | ENSG00000137965 | 10561 | IFI44 | Interferon-induced protein 44 | 6.7 | 1.50E-09 |
| 7 | ENSG00000088827 | 6614 | SIGLEC1 | Sialic acid binding Ig-like lectin 1, sialoadhesin | 3.6 | 3.80E-09 |
| 8 | ENSG00000166664 | 89832 | CHRFAM7A | Transfected gene | 55.4 | 7.80E-09 |
| 9 | ENSG00000166104 | 102466227 | MIR7162 | Micro RNA 7162 | 40.6 | 9.50E-07 |
| 10 | ENSG00000105655 | 51477 | ISYNA1 | Inositol-3-phosphate synthase 1 | 9.1 | 1.70E-06 |
| 11 | ENSG00000119922 | 3433 | IFIT2 | Interferon-induced protein tetratricopeptide repeats 2 | 3.6 | 2.20E-06 |
| 12 | ENSG00000206337 | 10866 | HCP5 | HLA complex P5 | 12 | 6.40E-06 |
| 13 | ENSG00000137959 | 10964 | IFI44L | Interferon-induced protein 44-like | 4.9 | 4.00E-05 |
| 14 | ENSG00000185745 | 3434 | IFIT1 | Interferon-induced protein tetratricopeptide repeats 1 | 3.9 | 5.20E-05 |
| 15 | ENSG00000183098 | 10082 | GPC6 | Glypican 6 | 5.1 | 6.30E-05 |
| 16 | ENSG00000170365 | 4086 | SMAD1 | SMAD family member 1 | 3.8 | 8.90E-05 |
| 17 | ENSG00000179796 | 116135 | LRRC3B | Leucine rich repeat containing 3B | 4.6 | 0.0002 |
| 18 | ENSG00000133106 | 94240 | EPSTI1 | Epithelial stromal interaction 1 | 3.3 | 0.0002 |
| 19 | ENSG00000165949 | 3429 | IFI27 | Interferon-induced protein 27 | 8.1 | 0.0006 |
| 20 | ENSG00000081923 | 5205 | ATP8B1 | ATPase, aminophospholipid transporter, type 8b member 1 | 0.31 | 0.0006 |
|
| ||||||
| Downregulated genes | ||||||
|
| ||||||
| Ensmbl | Entrez | Gene | Gene name or description | Δ | p | |
|
| ||||||
| 21 | ENSG00000174099 | 253827 | MSRB3 | Methionine sulfoxide reductase B3 | 0.37 | 1.80E-07 |
| 22 | ENSG00000156515 | 3098 | HK1 | Hexokinase 1 | 0.42 | 8.60E-07 |
| 23 | ENSG00000100060 | 4242 | MFNG | MFNG O-fucosyl 3-β-N-acetylglucosaminyl-transferase | 0.3 | 1.30E-06 |
| 24 | ENSG00000100234 | 7078 | TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.51 | 1.40E-06 |
| 25 | ENSG00000182263 | 55137 | FIGN | Fidgetin | 0.08 | 3.30E-06 |
| 26 | ENSG00000165659 | 1602 | DACH1 | Dachshund family transcription factor 1 | 0.46 | 1.50E-05 |
| 27 | ENSG00000134824 | 9415 | FADS2 | Fatty acid desaturase 2 | 0.58 | 0.0002 |
| 28 | ENSG00000126767 | 2002 | ELK1 | ELK1, member of ETS oncogene family | 0.42 | 0.0002 |
| 29 | ENSG00000144712 | 23066 | CAND2 | Cullin-associated and neddylation-dissociated 2 | 0.31 | 0.0006 |
| 30 | ENSG00000011600 | 7305 | TYROBP | TYRO protein tyrosine kinase binding protein | 0.59 | 0.0007 |