Table 1.
Patient characteristics at the day of enrollment.
| Adjunctive APC-treatmenta | No adjunctive APC-treatmentb | |
|---|---|---|
| Age, years | 47 (40.0/66.5)c | 64.5 (58.25/74.25)c |
| Number of patients | 5 | 4 |
| Sex distribution, male | 60% | 75% |
| Scores, points | ||
| APACHE II | 25 (23.5/28.5)c | 25 (19.75/34.75)c |
| SAPS | 50 (49/59.5)c | 62 (47.75/67.75)c |
| ISTH | 3 (3/3)c | 3 (3/3)c |
| SOFA | 9 (8/11.5)c | 11 (9.25/12.75)c |
| Pathogen | ||
| Gram-positive | 3 | 4 |
| Gram-negative | 2 | 0 |
| Focus | ||
| Lung | 2 | 2 |
| Abdomen | 2 | 3 |
| Urogenital | 2 | 1 |
| Various | 1 | 0 |
| Laboratory findings | ||
| Procalcitonin, ng/mL | 20.57 (4.79/33.09)c | 1.18 (0.37/29.66)c |
| Leukocytes, Gpt/L | 18.5 (4.4/37.25)c | 27.2 (4.25/40.75)c |
| Outcome | ||
| Length of stay at ICU, days | 8 (7/24)c | 13.5 (4/40.25)c |
| Length of stay at hospital, days | 34 (22/60)c | 19 (4.25/65.25)c |
| Mortality rate, % | 0 | 50 |
a
Patients who received APC (n = 5).
b
Patients with placebo (n = 4).
c
Data given as median (25th/75th percentile).