Table 1.

Induction of apoptosis by Stx in the 25 cell lines we tested^a.

Cell line	Induction of apoptosis by Stx	Tissue	Morphology	Organism
THP1	+++	Peripheral blood	Monocyte	H. sapiens
U937	−	Pleural effusion, lymphocyte, myeloid	Monocyte	H. sapiens
Raji	+	Lymphoblast	Lymphoblast	H. sapiens
K562	−	Bone marrow	Lymphoblast	H. sapiens
HL60	−	Peripheral blood	Myeloblastic	H. sapiens
KYO-1	−	Peripheral blood	Myeloblastic	H. sapiens
CCRF-CEM	−	Peripheral blood	Lymphoblast	H. sapiens
Jurkat	−	Peripheral blood	Lymphoblast	H. sapiens
HEL	−	Bone marrow	Lymphoblast	H. sapiens
MOLT4	−	T lymphoblast	Lymphoblast	H. sapiens
A549	−	Lung	Epithelial	H. sapiens
HeLa	−	Cervix	Epithelial	H. sapiens
HEK-293	−	Embryonic kidney	Epithelial	H. sapiens
Caco-2	−	Colon	Epithelial-like	H. sapiens
U-2 OS	−	Bone	Epithelial	H. sapiens
HT1080	−	Connective tissue	Epithelial	H. sapiens
MBEC2, 4, 6, 7	−	Brain	Endothelial	M. musculus
M1	−	Bone marrow	Myeloblast	M. musculus
SP2/0	−	Spleen	Lymphoblast-like	M. musculus
P388	−	Monocyte, macrophage	Lymphoblast	M. musculus
Vero	+	Kidney	Epithelial	C. aethiops
COS-1	−	Kidney	Fibroblast	C. aethiops

^aCells were treated with either 400 ng/ml Stx1 or Stx2 for up to 48 h, and apoptotic morphological changes were monitored.