Fig A2.
Relationship between percentage change in maximum standardized uptake value (SUVmax) at week 1 and best percentage change of target lesions. Each individual patient is plotted according to percentage change in SUVmax by [18F]fluorodeoxyglucose positron emission tomography/computed tomography (CT) comparing baseline and week 1 on the y-axis and according to best percentage change in sum of longest dimensions of target lesions relative to baseline by CT imaging on the x-axis. Seven patients were considered RECIST nonresponders despite reductions of more than 30% in the sum of target lesions. Of these patients, six had an initial partial response that was not confirmed on subsequent imaging 8 weeks later: one had stable disease > 24 weeks and one had stable disease on initial restaging and more than 30% on second restaging but in the setting of a new lesion and was therefore deemed a nonresponder.