Table 2.
Impacts of incident fracture on health related quality of life measures and general health.
| Assessment | SF-36 physical function score | SF-36 vitality scale | Quality of life (EQ-index) | General health (≥good) | ||||
|---|---|---|---|---|---|---|---|---|
| Coefficient (95% CI) | Coefficient (95% CI) | Coefficient (95% CI) | Odds ratio (95% CI) | |||||
| All fractures included | Minor fractures excluded§ | All fractures included | Minor fractures excluded§ | All fractures included | Minor fractures excluded§ | All fractures included | Minor fractures excluded§ | |
| Univariate analysis | ||||||||
| Prior to incident fracture | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 | 1.00 |
| The 1st year after incident fracture | −3.3∗∗
(−5.5 to −1.0) |
−4.7∗∗∗
(−7.5 to −1.9) |
−4.1∗∗∗
(−6.0 to −2.1) |
−3.9∗∗∗
(−6.2 to −1.7) |
−0.04∗∗∗
(−0.07 to −0.02) |
−0.05∗∗∗
(−0.08 to −0.02) |
0.80∗
(0.67 to 0.96) |
0.78 (0.58 to 1.05) |
| The 2nd year after incident fracture | −5.0∗∗∗
(−7.6 to −2.3) |
−5.9∗∗∗
(−9.2 to −2.7) |
−0.9 (−3.0 to 1.2) |
−0.4 (−2.7 to 2.0) |
−0.01 (−0.03 to 0.01) |
−0.01 (−0.04 to 0.02) |
0.86 (0.69 to 1.07) |
0.88 (0.60 to 1.28) |
| The 3rd year after incident fracture | −3.7 (−7.6 to 0.1) |
−3.2 (−7.3 to 1.0) |
−1.1 (−4.3 to 2.2) |
−0.7 (−4.5 to 3.1) |
−0.03 (−0.06 to 0.01) |
−0.04 (−0.09 to 0.00) |
0.97 (0.71 to 1.32) |
0.72 (0.41 to 1.26) |
|
| ||||||||
| Multivariable analysis ∧ | ||||||||
| Prior to incident fracture | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 | 1.00 |
| The 1st year after incident fracture | −1.6 (−4.2 to 1.0) |
−2.9 (−6.1 to 0.3) |
−3.0∗∗
(−5.1 to −0.8) |
−2.6∗∗
(−5.2 to −0.1) |
−0.03∗
(−0.06 to −0.00) |
−0.04∗
(−0.07 to −0.00) |
0.97 (0.78 to 1.21) |
0.95 (0.66 to 1.38) |
| The 2nd year after incident fracture | −3.0∗
(−5.6 to −0.5) |
−3.8∗∗
(−6.8 to −0.8) |
−0.8 (−3.2 to 1.6) |
0.03 (−2.6 to 2.7) |
−0.02 (−0.04 to 0.01) |
−0.02 (−0.05 to 0.01) |
0.92 (0.70 to 1.19) |
1.10 (0.69 to 1.73) |
| The 3rd year after incident fracture | 0.2 (−4.1 to 4.4) |
1.5 (−2.6 to 5.6) |
0.6 (−3.1 to 4.3) |
1.2 (−3.1 to 5.5) |
−0.02 (−0.06 to 0.02) |
−0.03 (−0.09 to 0.02) |
1.04 (0.72 to 1.50) |
0.84 (0.44 to 1.61) |
§Minor fractures: hand, foot, toe, and digital fractures.
∧Adjusted for age, private insurance, tertiary education, history of prior fracture after 45 years, body mass index, prior year weight loss ≥5 kgs, any comorbidity, current smoking, drinking ≥7 drinks/week, and number of falls in the prior year.
∗ P value ≤0.05.
∗∗ P value ≤0.01.
∗∗∗ P value ≤0.001.