Table 3.
Changes in health related quality of life measures according to fracture location.
| Fracture type | Quality of life measure | Assessment time | No. | Mean | Mean difference from baseline (95% CI) |
|---|---|---|---|---|---|
| Hip or vertebral (n = 26) |
SF-36 physical function score | Prior to incident fracture | 26 | 49.8 | 0 |
| 1 year after fracture | 24 | 53.2 | 0.1 (−10.2, 10.4) | ||
| 2 years after fracture | 13 | 56.2 | −9.4 (−17.9, −0.9)∗ | ||
| SF-36 vitality scale |
Prior to incident fracture | 25 | 51.1 | 0 | |
| 1 year after fracture | 24 | 48.9 | −1.2 (−9.3, 6.9) | ||
| 2 years after fracture | 12 | 62.5 | 1.2 (−7.8, 10.3) | ||
| EQ-5D | Prior to incident fracture | 25 | 0.67 | 0 | |
| 1 year after fracture | 23 | 0.58 | −0.10 (−0.19, −0.01)∗ | ||
| 2 years after fracture | 13 | 0.76 | −0.03 (−0.12, 0.06) | ||
| General health§ | Prior to incident fracture | 26 | 3.1 | 0 | |
| 1 year after fracture | 25 | 3.4 | 0.36 (0.10, 0.62)∗∗ | ||
| 2 years after fracture | 13 | 2.9 | 0.23 (−0.13, 0.59) | ||
|
| |||||
| Nonhip, nonvertebral (n = 212) |
SF-36 physical function score | Prior to incident fracture | 207 | 75.6 | 0 |
| 1 year after fracture | 200 | 72.9 | −2.4 (−4.7, −0.0)∗ | ||
| 2 years after fracture | 132 | 72.9 | −3.9 (−7.2, −0.7) | ||
| SF-36 vitality scale |
Prior to incident fracture | 206 | 59.6 | 0 | |
| 1 year after fracture | 199 | 56.5 | −3.0 (−5.3, −0.7)∗ | ||
| 2 years after fracture | 129 | 61.3 | −0.2 (−3.3, 3.0) | ||
| EQ-5D | Prior to incident fracture | 201 | 0.78 | 0 | |
| 1 year after fracture | 197 | 0.77 | −0.02 (−0.04, 0.01) | ||
| 2 years after fracture | 125 | 0.80 | 0.01 (−0.02, 0.04) | ||
| General health§ | Prior to incident fracture | 208 | 2.6 | 0 | |
| 1 year after fracture | 206 | 2.6 | 0.06 (−0.03, 0.16) | ||
| 2 years after fracture | 132 | 2.5 | 0.53 (−0.06, 0.17) | ||
|
| |||||
| Multiple regions∧
(n = 28) |
SF-36 physical function score | Prior to incident fracture | 28 | 71.2 | 0 |
| 1 year after fracture | 27 | 63.0 | −7.4 (−18.4, 3.7) | ||
| 2 years after fracture | 18 | 63.1 | −6.03 (−14.46, 2.39) | ||
| SF-36 vitality scale |
Prior to incident fracture | 28 | 53.4 | 0 | |
| 1 year after fracture | 28 | 49.6 | −3.7 (−11.1, 3.6) | ||
| 2 years after fracture | 18 | 53.8 | −1.0 (−4.8, 2.7) | ||
| EQ-5D | Prior to incident fracture | 28 | 0.80 | 0 | |
| 1 year after fracture | 27 | 0.67 | −0.13 (−0.23, −0.03)∗ | ||
| 2 years after fracture | 17 | 0.75 | −0.07 (−0.17, 0.03) | ||
| General health§ | Prior to incident fracture | 28 | 2.7 | 0 | |
| 1 year after fracture | 27 | 2.7 | 0.00 (−2.45, 2.45) | ||
| 2 years after fracture | 19 | 2.7 | 0.00 (−0.32, 0.32) | ||
∧An incident resulting fracture in multiple regions.
∗ P value ≤0.05.
∗∗ P value ≤0.01.
§Self-rated general health using 5-point Likert scales (excellent, very good, good, fair, or poor).