FIG 8.

Mice colonized with A. fumigatus hyphae exhibit signs of an early, limited allergic response. (A) Time course of the levels of IgE from serum measured by ELISA. Bars represent the means ± standard errors of the means from at least three independent experiments (total, n = 5 to 34 per group). (B) Respiratory system resistance and elastance were measured in mice infected with Af beads or sterile beads at 7, 14, and 28 days postinfection using a FlexiVent ventilator. Data points represent the means ± standard errors of the means from 5 to 8 mice per group per time point. *, P < 0.05; **, P < 0.005; ***, P < 0.001, compared to mice infected with sterile beads at the same time point in panel A, or as indicated in panel B.