Fig. 2.
Effect of adenosine receptor antagonists on neutrophil chemotaxis in the presence of adenosine. The effect of the A1 antagonist DPCPX 10− 7 M (A and B), the A2 antagonist SCH58261 10− 7 M (C and D) and the A3 antagonist MRS 1334 10− 7 M (E and F) on neutrophil migration to IL-8 10− 9 M over 30 min in the presence or absence of adenosine 10− 8 M (A, C and E; n = 6) or adenosine 10− 5 M (B, D and F; n = 7). All inhibitors were assessed within the same experiment but are divided into different panels for clarity. Results are presented as mean ± SEM and analysed for statistical significance using one-way analysis of variance followed by Bonferroni's test for multiple comparisons. *p < 0.05 and **p < 0.01.